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ACE2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 21115-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16830725

  • 121.38€ / 20µL
Expédition estimée: 04-10-2022
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Description

Description

This antibody is specific to ACE2.

Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.
Spécification

Spécification

ACE2
Polyclonal
Unconjugated
ACE2
ACE related carboxypeptidase, ACE2, ACEH, Angiotensin converting enzyme 2, Metalloprotease MPROT15
Rabbit
Antigen Affinity Chromatography
RUO
302668, 59272, 70008
-20°C
Liquid
Western Blot, Immunoprecipitation
0.43 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q5EGZ1, Q8R0I0, Q9BYF1
ACE2
ACE2 Fusion Protein Ag15455
20 μL
Primary
Rat, Mouse, Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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