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ACROBiosystems ActiveMax™ Human IL-4 Protein, Tag Free

Marque:  ACROBiosystems IL4-H4218-20UG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15867047

  • 181.58€ / 20µg
Date d’expédition estimée: 24-12-2021

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Description

Description

Interleukin-4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells to Th2 cells). In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Recently, researcher found that the cytokine IL-4 plays a key role in development of innate CD8+ T cells in the thymus of several gene-deficient mouse strains, including Itk, KLF2, CBP and Id3, without previous exposure to antigen.

This protein carries no "e;tag"e;. The protein has a calculated MW of 15.0 kDa. The protein migrates as 15 kDa and 19 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

AAH67514
HEK293
Human
15.0 kDa
20 µg
His 25 - Ser 153
IL4,BCGF1,BSF1
Unconjugated
PBS, pH7.4
Less than 0.1 EU / µg by the LAL method.
ActiveMax™ Cytokines
Powder
>90% as determined by SDS-PAGE
ActiveMax™ Human IL-4, Tag Free (IL4-H4218) is expressed from human 293 cells (HEK293). It contains AA His 25 - Ser 153 (Accession # P05112-1).
-20°C
IL-4
Tag Free
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