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AEG-1/MTDH Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
140.00€ - 399.00€
Spécification
Antigène | AEG-1/MTDH |
---|---|
Concentration | 0.35 mg/mL |
Applications | Western Blot, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin) |
Classification | Polyclonal |
Conjugué | Unconjugated |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
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Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
16812264
|
Proteintech
13860-1-AP-20UL |
20 μL |
140.00€
20µL |
Expédition estimée: 06-05-2024 Connectez-vous pour voir le stock disponible |
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16802264
|
Proteintech
13860-1-AP-150UL |
150 μL |
399.00€
150µL |
Expédition estimée: 06-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
This antibody got two bands about 70 kDa and 80 kDa in western blotting, possibly due to posttranslational modification. This antibody is specific to AEG-1/MTDH.
Metadherin (Metastasis adhesion protein), also known as MTDH, LYsine-RIch CEACAM1 co-isolated (LYRIC), is a novel protein that localizes with the tight junction proteins ZO-1 and occludin in polarized epithelial cells. At the tight junction, it acts not as a structural component, but is rather recruited during the maturation of the tight junction complex. Metadherin is overexpressed in breast cancer tissue and breast tumor xenografts, while much lower levels are expressed in normal breast tissue. Metadherin binds to lung vasculature, one of the four common sites of breast cancer metastasis, through a C-terminal segment in the extracellular domain; blocking this lung-homing domain with antibodies or inhibiting metadherin with siRNA has been reported to inhibit breast cancer metastasis.Spécification
AEG-1/MTDH | |
Western Blot, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin) | |
Unconjugated | |
Rabbit | |
Mouse, Rat, Human | |
Q80WJ7, Q86UE4, Q9Z1W6 | |
170910, 67154, 92140 | |
AEG-1/MTDH-Specific Fusion Protein Ag4840 | |
Primary | |
-20°C | |
MTDH |
0.35 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
3D3, 3D3/LYRIC, AEG 1, AEG1, LYRIC, LYRIC/3D3, metadherin, Metastasis adhesion protein, MTDH, Protein LYRIC | |
Mtdh | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |