missing translation for 'onlineSavingsMsg'
Learn More

Casein Kinase IIα/α Mouse, Unlabeled, Clone: 31, BD

Mouse Monoclonal Antibody

Marque:  BD Biosciences 611610

Informations supplémentaires : Poids : 0.01100kg

 Afficher plus de versions de ce produit

Code produit. 15845989

  • 337.44€ / 1 kit
Expédition estimée: 01-03-2023
pour voir le stock disponible 

Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!


Description

Description

Casein kinase II (CKII, CK2) is a pleiotropic, ubiquitous, and constitutively active Ser/Thr kinase that utilizes both ATP and GTP as phosphoryl donors to catalyze the phosphorylation of numerous protein substrates. It has been implicated in DNA replication, control of metabolism, and regulation of transcription and translation. CKII is a messenger independent kinase due to the fact that its activity is not affected by factors that regulate other protein kinases (e.g. cAMP, Ca2+, diacylglycerol). It is composed of two catalytic (α and α′) subunits and two regulatory (β) subunits. The β subunits stabilize the holoenzyme and enhance the activity of the α subunits. Although the enzyme exists as a tetramer, the free α/α′ subunits are catalytically active by themselves and are present in cells under some conditions. The α and α′ subunits (85% homologous) are encoded by distinct genes and have been detected in multiple species including human, bovine, and avian. CKII is found primarily in the nucleus in dividing cells, but can be detected in the cytoplasm in quiescent cells. Thus, CKII activity is required for cell cycle progression and other essential signal transduction events.

Host Species: Mouse
Clone: 31
Isotype: IgG1
Species Reactivity [for Features Main]: Rat
Immunogen: Rat Casein Kinase II α aa. 1-123

Immunofluorescence, Western Blotting

Spécification

Spécification

Casein Kinase IIα/α
Monoclonal
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Rat Casein Kinase II α aa. 1-123
50 μg
Cell Biology
Rat, Mouse, Human
IgG1
Western Blot
31
Unconjugated
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
Vidéos
FDS
Documents

Documents

Certificats
Promotions

Promotions

For Research Use Only.