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CD11b Rat anti-Mouse, APC-Cy7, Clone: M1/70, BD

Rat Monoclonal Antibody

Marque:  BD Biosciences 561039

Informations supplémentaires : Poids : 0.01000kg

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Code produit. 15870709

  • 183.60€ / 1 pièce
Date d’expédition estimée: 15-12-2021

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Description

Description

The M1/70 antibody reacts with the 170kDa α[M] chain of Mac-1 (CD11b/CD18, α[M]β[2] integrin), also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, myeloid-derived dendritic cells, natural killer cells, microglia, and B-1 cells. Mac-1 expression is rapidly up-regulated on neutrophils after activation, in the same time period that CD62L (L-selectin) is shed from the cell surface. M1/70 antibody reportedly blocks cell adherence and C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes, polymorphonuclear leukocytes, and NK cells has been reported. This antibody is routinely tested by flow cytometric analysis (≤0.25 μg/million cells).

Host Species: Rat
Clone: M1/70
Isotype: IgG2b, κ
Species Reactivity: Mouse
Immunogen: Mouse splenic Cells

Flow Cytometry

Spécification

Spécification

CD11b
M1/70
APC-Cyanine7
Aqueous buffered solution containing ≤0.09% sodium azide.
Rat
IgG2b, κ
RUO
Primary
Human, Murine
Flow Cytometry
0.2mg/mL
Itgam; Integrin alpha-M; Ly-40; Mac-1a; Mac-1 alpha; CR3A; CR-3 alpha chain
Affinity Purified
Mouse Splenic Cells
25μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Vidéos
FDS
Documents
Certificats
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For Research Use Only.