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CD1d Mouse anti-Human, Brilliant Violet 510, Clone: CD1d42 (also known as 42.1), BD

Mouse Monoclonal Antibody

Marque:  BD Biosciences 563506

Informations supplémentaires : Poids : 0.01000kg

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Code produit. 15872839

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Description

Description

The CD1d42 monoclonal antibody recognizes CD1d. Cell surface CD1d is structurally homologous to Class I MHC molecules. It consists of a glycosylated type I transmembrane α chain (43-49 kDa) that is non-covalently associated with β2-microglobulin. CD1d is a member of the CD1 family of molecules, which belong to the immunoglobulin superfamily. Sequence homology data classifies the CD1 molecules into two groups. Group 1 includes CD1a, CD1b and CD1c molecules; group 2 includes CD1d molecules and their homologs in other species. CD1d is expressed on cortical thymocytes, B cells, dendritic cells, monocytes, and some nonlymphoid cells including intestinal epithelial cells, hepatocytes and keratinocytes. It is not expressed on resting mature T cells. Studies suggest that CD1d participates in lipid antigen presentation to CD1d-restricted NKT cells.

The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. With an Ex Max of 405-nm and Em Max at 510-nm, BD Horizon™ BV510 can be excited by the violet laser and detected in the BD Horizon™ V500 (525/50-nm) filter set. BD Horizon™ BV510 conjugates are useful for the detection of dim markers off the violet laser.

Spécification

Spécification

CD1d
Monoclonal
Brilliant Violet 510
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Human CD1d Recombinant Protein
100 Tests
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
CD1d42 (also known as 42.1)
R3; R3G1; HMC class I antigen-like glycoprotein CD1D
Mouse
Affinity Purified
RUO
Human
IgG1 κ
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