CD69 Hamster anti-Mouse, PE, Clone: H1.2F3, BD
Hamster Monoclonal Antibody
Marque: BD Biosciences 561932
Informations supplémentaires : Poids : 0.01000kg
The H1.2F3 monoclonal antibody specifically binds to CD69 (Very Early Activation antigen), an 85 kDa disulfide-linked homodimer of differentially glycosylated subunits. CD69 is a C-type lectin, most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules. Its expression is rapidly induced upon activation of lymphocytes (T, B, NK, and NK-T cells), neutrophils, and macrophages. CD69 is expressed also on thymocytes that are undergoing positive selection; its role in that process is unclear. H1.2F3 mAb augments PMA-induced T-cell stimulation and IFN-γ-induced macrophage stimulation. IL-2-activated NK cells express CD69, and H1.2F3 mAb induces redirected lysis of FcR-bearing target cells by NK cells.
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|VEA; Very Early Activation Antigen; AIM; Activation Induced Molecule|
|Mouse Dendritic Epidermal T Cell Line Y245|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
For Research Use Only.