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CD69 Hamster anti-Mouse, PE, Clone: H1.2F3, BD

Hamster Monoclonal Antibody

Marque:  BD Biosciences 555318

Informations supplémentaires : Poids : 0.01000kg

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Code produit. 15878058

  • 675.00€ / 1 pièce
Expédition estimée: 23-04-2024
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Description

Description

The In-1 monoclonal antibody specifically binds to CD74, the MHC class II-associated Invariant chain (Ii), expressed in I-A+ cell populations. Although it is predominantly expressed intracellularly, it has also been detected on the cell surface of some B-cell lines and at low levels on a small number of B lymphocytes. In the mouse, alternatively spliced transcripts encode 31-kDa and 41-kDa isoforms, and the cell-surface CD74 has a chondroitin sulfate side chain which allows it to interact with CD44. CD74 is directly involved in the intracellular transport of MHC class II molecules and antigen presentation, and it affects the maturation of T and B lymphocytes.

Spécification

Spécification

CD74
Monoclonal
0.5mg/mL
Cd74; CLIP; Ii; Ia-associated invariant chain; Ia-GAMMA; DHLAG; HG2A; HLADG
Rat
Affinity Purified
RUO
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
IN-1
FITC
Aqueous buffered solution containing ≤0.09% sodium azide.
ATL mouse lymphocytes and B10A mouse-derived CH1 B-cell lymphoma
0.5 mg
Immunology
Mouse
IgG2b κ
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For Research Use Only.