missing translation for 'onlineSavingsMsg'
Learn More

CXCR5 Rat anti-Human, BB515, Clone: RF8B2, BD

Rat Monoclonal Antibody

Marque:  BD Biosciences 564625

Informations supplémentaires : Poids : 0.01000kg

 Afficher plus de versions de ce produit

Code produit. 15873759

  • 196.86€ / 1 pièce
Date d’expédition estimée: 23-12-2021

Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!


Description

Description

The RF8B2 monoclonal antibody specifically binds to the human CXC chemokine receptor, CXCR5. CXCR5 (also known as CD185, BLR-1 NLR and MDR15), a seven transmembrane, G-protein-coupled receptor, is the specific receptor for CXC chemokine, CXCL13/BLC/BCA-1. In peripheral blood, CXCR5 expression is restricted to B lymphocytes and a small subset of CD4+ and CD8+ lymphocytes. The restricted expression pattern of CXCR5 on B cells and follicular T helper cells (Tfh) suggests that this receptor functions as a regulator of B and T cell migration. Stimulation of T cells with anti-CD3 monoclonal antibody leads to the down-regulation of CXCR5.

The antibody was conjugated to BD Horizon BB515 which was developed exclusively by BD Biosciences. With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (eg, 530/30-nm filter). This dye provides a much brighter alternative to FITC with less spillover into the PE detector.

Spécification

Spécification

CXCR5
RF8B2
CD185; Chemokine C-X-C motif receptor 5; BLR1; MDR-15
Affinity Purified
Human CXCR5
25 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
BB515
Aqueous buffered solution containing ≤0.09% sodium azide
Rat
IgG2b, κ
RUO
Primary
Human
Vidéos
FDS
Documents
Certificats
Promotions

Promotions

For Research Use Only.