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Cyclin E Mouse anti-Human, Unlabeled, Clone: HE12, BD

Mouse Monoclonal Antibody

Marque:  BD Biosciences 551160

Informations supplémentaires : Poids : 0.02000kg

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Code produit. 15876558

  • 462.06€ / 1 pièce
Date d’expédition estimée: 29-12-2021

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Description

Description

Cyclins and cyclin-dependent kinases (cdks) are evolutionarily conserved proteins that are essential for cell-cycle control in eukaryotes. Cyclins (regulatory subunits) bind to cdks (catalytic subunits) to form complexes that regulate the progression of the cell cycle. These complexes are regulated by activating and inhibitory phosphorylation events, as well as by interactions with small proteins that bind to cyclins, cdks, or cyclin-cdk complexes, e.g., p21 and p27 [Kip1]. Cyclin E is expressed in G1 and associates with cdk2 to form an active kinase where it plays an important role in the regulation of the G1/S restriction checkpoint in the cell cycle. Abberant expression of cyclin E has been reported to be associated with the oncogenic transformation of cells. This antibody has been reported not to cross-react with mouse cyclin E.

Spécification

Spécification

Cyclin E
HE12
Affinity Purified
IgG1
RUO
Store undiluted at -20°C.
Monoclonal
Western Blot
Unconjugated
Mouse
150μg
Cell Biology
Primary
Human
Vidéos
FDS
Documents
Certificats
Promotions

Promotions

For Research Use Only.