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Cyclin E Mouse anti-Human, Unlabeled, Clone: HE12, BD
Mouse Monoclonal Antibody
316.00€ - 576.00€
Spécification
Antigène | Cyclin E |
---|---|
Clone | HE12 |
Applications | Western Blot |
Classification | Monoclonal |
Conjugué | Unconjugated |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
---|---|---|---|---|---|---|---|---|---|
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
10537085
|
BD Biosciences
551159 |
50 μg |
316.00€
1 pièce |
Expédition estimée: 16-05-2024 Connectez-vous pour voir le stock disponible |
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15876558
|
BD Biosciences
551160 |
150 μg |
Cet article est actuellement indisponible ou discontinu.
Veuillez consulter la page produit pour de possible alternative dans l’onglet |
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Description
Cyclins and cyclin-dependent kinases (cdks) are evolutionarily conserved proteins that are essential for cell-cycle control in eukaryotes. Cyclins (regulatory subunits) bind to cdks (catalytic subunits) to form complexes that regulate the progression of the cell cycle. These complexes are regulated by activating and inhibitory phosphorylation events, as well as by interactions with small proteins that bind to cyclins, cdks, or cyclin-cdk complexes, e.g., p21 and p27 [Kip1]. Cyclin E is expressed in G1 and associates with cdk2 to form an active kinase where it plays an important role in the regulation of the G1/S restriction checkpoint in the cell cycle. Abberant expression of cyclin E has been reported to be associated with the oncogenic transformation of cells. This antibody has been reported not to cross-react with mouse cyclin E.
Spécification
Cyclin E | |
Western Blot | |
Unconjugated | |
RUO | |
Human | |
Primary | |
Store undiluted at -20°C. |
HE12 | |
Monoclonal | |
Mouse | |
Cell Biology | |
IgG1 | |
Affinity Purified |
For Research Use Only.