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HLA-DR Mouse anti-Human, BUV661, Clone: G46-6, BD

Mouse Monoclonal Antibody

Marque:  BD Biosciences 565073

Informations supplémentaires : Poids : 0.01100kg

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Code produit. 15874059

  • 591.60€ / 1 pièce
Date d’expédition estimée: 23-12-2021

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Description

Description

The G46-6 monoclonal antibody specifically binds to HLA-DR, a major histocompatibility complex (MHC) class II antigen. HLA-DR antigens are encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6. HLA-DR is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kDa) and a β subunit (27 kDa) expressed primarily on antigen presenting cells: B cells, dendritic cells, monocytes, macrophages, and thymic epithelial cells. HLA-DR is also expressed on activated T cells. This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4-positive T cells.

For optimal and reproducible results, BD Horizon Brilliant Stain Buffer should be used anytime two or more BD Horizon Brilliant dyes are used in the same experiment. Fluorescent dye interactions may cause staining artifacts which may affect data interpretation. The BD Horizon Brilliant Stain Buffer was designed to minimize these interactions. More information can be found in the Technical Data Sheet of the BD Horizon Brilliant Stain Buffer (Cat. No. 563794).

Due to spectral differences between labeled cells and beads, using BD™ CompBeads can result in incorrect spillover values when used with BD Horizon BUV661 reagents. Therefore, the use of BD CompBeads or BD CompBeads Plus to determine spillover values for these reagents is not recommended. Different BUV661 reagents (eg, CD4 vs. CD45) can have slightly different fluorescence spillover therefore, it may also be necessary to use clone-specific compensation controls when using these reagents.

Spécification

Spécification

HLA-DR
G46-6
MHC class II antigen; HLA class II histocompatibility antigen
Affinity purified
IgG2a, κ
RUO
Primary
Baboon, Cynomolgus, Human, Rhesus Monkey
Flow Cytometry
Brilliant Ultraviolet 661
Aqueous buffered solution containing ≤0.09% sodium azide
Mouse
100 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Vidéos
FDS
Documents
Certificats
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For Research Use Only.