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IL-17A Rat anti-Mouse, Alexa Fluor 647, Clone: TC11-18H10, BD

Rat Monoclonal Antibody

Marque:  BD Biosciences 560224

Informations supplémentaires : Poids : 0.00800kg

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Code produit. 15850029

  • 231.42€ / 1 pièce
Expédition estimée: 22-02-2023
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Description

Description

The TC11-18H10 antibody reacts with recombinant and natural mouse IL-17A proteins. IL-17A, also known as CTLA-8, is a T cell-derived cytokine that promotes inflammatory responses. Mouse IL-17A is a proinflammatory cytokine that can induce the release of IL-6 by mouse stromal cells. It has been shown to support the growth of hemopoietic progenitors in vitro; it can also stimulate granulopoiesis in vivo. The TC11-18H10 antibody has been reported to neutralize IL-17A activity. Recent studies have shown that IL-17A is produced by a unique subset of Th17 cells that develop along a pathway distinct from the Th1- and Th2- cell differentiation pathways. The mouse IL-17A cDNA was isolated from a cDNA library generated from TCRαβ+CD4-CD8- thymocytes.

Host Species: Rat
Clone: TC11-18H10
Isotype: IgG1 κ
Species Reactivity: Mouse
Immunogen: Recombinant Mouse IL-17A Protein

Intracellular Staining

Spécification

Spécification

IL-17A
Monoclonal
0.2mg/mL
Aqueous buffered solution containing ≤0.09% sodium azide.
Recombinant Mouse IL-17A Protein
25 μg
Immunology
Mouse
IgG1 κ
Flow Cytometry
TC11-18H10
Alexa Fluor 647
Rat
Affinity Purified
RUO
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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For Research Use Only.