missing translation for 'onlineSavingsMsg'
Learn More

Neurotensin Receptor 3 (NTR3) Mouse, Unlabeled, Clone: 48, BD

Mouse Monoclonal Antibody

Marque:  BD Biosciences 612100

Informations supplémentaires : Poids : 0.01000kg

 Afficher plus de versions de ce produit

Code produit. 15876089

  • 330.00€ / 1 kit
Expédition estimée: 22-04-2024
pour voir le stock disponible 

Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!


Description

Description

Neurotensin (NT) is a neuropeptide that modulates dopaminergic transmission, triggers analgesic responses, induces hypotension, decreases gastric acid secretion, and activates lipid digestion. NT is a ligand for NT receptors, which include both G-protein coupled and non-G-protein coupled receptors. Neurotensin Receptor 3 (NTR3) is a non-G-protein coupled receptor that has a lumenal domain homologous to sorting proteins, and a short cytoplasmic tail homologous to mannose-6-phosphate/IGF-II receptor. NTR3 was also identified as sortilin/gp95, a component of GLUT4 vesicles in adipocytes that has been implicated in lipoprotein lipase degradation. NTR3 mRNA is expressed in brain, skeletal muscle, heart, and adipocytes. NTR3 mature protein has 44 N-terminal amino acid residues cleaved off, which may facilitate ligand binding to the receptor. Cellular localization of NTR3 is in the Golgi compartment and vesicles, as well as on the cell surface. In addition to roles in neuropeptide and lipoprotein degradation, NTR3 may also be involved in receptor protein sorting. Thus, NTR3 is a multifunctional transmembrane protein that acts as both a intracellular sorting receptor and extracellular ligand-binding receptor.

Immunofluorescence, Western Blotting

Spécification

Spécification

Neurotensin Receptor 3 (NTR3)
Monoclonal
250μg/mL
NTR3
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
Western Blot
48
Unconjugated
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Human Neurotensin Receptor 3 aa. 300-422
50 μg
Cell Biology
Canine, Chicken, Human, Mouse, Rat
IgG1
Suggestions de produits

Suggestions de produits

Vidéos
FDS
Documents

Documents

Certificats
Promotions

Promotions

For Research Use Only.