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Phospho-Separase (Ser801) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marque: Invitrogen PA538245
Code nomenclature Nacres: NA.41
Informations supplémentaires : Poids : 0.00900kg
Description
Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 by ESPL1, or separase, which initiates the final separation of sister chromatids .Spécification
| Phospho-Separase (Ser801) | |
| Polyclonal | |
| Unconjugated | |
| ESPL1 | |
| ESP1, FLJ46492, KIAA0165, caspase-like protein ESPL1, extra spindle poles like 1, extra spindle poles-like 1 protein, separin | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 105988, 9700 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q14674, P60330 | |
| ESPL1 | |
| A synthetic phosphopeptide derived from human SEPARASE around the phosphorylation site of Ser801 (N-S-SP-P-V) | |
| 100 μg | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |