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PKA[C] Mouse, Unlabeled, Clone: 5B, BD
Mouse Monoclonal Antibody
Marque: BD Biosciences 610980
Informations supplémentaires : Poids : 0.01000kg
Description
cAMP-dependent Protein Kinase (PKA) is composed of two distinct subunits: catalytic (C) and regulatory (R). Four regulatory subunits have been identified: RIα, RIβ, RIIα, and RIIβ. These subunits define type I and II cAMP-dependent protein kinases. Following binding of cAMP, the regulatory subunits dissociate from the catalytic subunits, rendering the enzyme active. Type I and type II holoenzymes have three potential C subunits (Cα, Cβ, or Cγ). Type II PKA can be distinguished by autophosphorylation of the R-subunits, while type I PKA binds Mg/ATP with high affinity. The levels of expression of the different subunits vary according to cell and tissue type.
Immunofluorescence, Western Blotting
Spécification
PKA[C] | |
Monoclonal | |
250μg/mL | |
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
Human PKA[Cα] subunit aa. 18-347 | |
50 μg | |
Cell Biology | |
Canine, Human, Mouse, Rat | |
IgG2b |
Western Blot | |
5B | |
Unconjugated | |
Mouse | |
Affinity Purified | |
RUO | |
Primary | |
Store undiluted at -20°C. |
For Research Use Only.