missing translation for 'onlineSavingsMsg'
Learn More
Learn More
PKA RIIβ Mouse, Unlabeled, Clone: 45, BD
Mouse Monoclonal Antibody
325.00€ - 650.00€
Spécification
| Antigène | PKA RIIβ |
|---|---|
| Clone | 45 |
| Concentration | 250μg/mL |
| Applications | Western Blot |
| Classification | Monoclonal |
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|---|---|---|---|---|---|---|---|---|---|
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|
15875549
|
BD Biosciences
610625 |
50 μg |
325.00€
1 kit |
Expédition estimée: 16-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
|
15885549
|
BD Biosciences
610626 |
150 μg |
650.00€
1 kit |
Expédition estimée: 16-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
cAMP-dependent Protein Kinase (PKA) is composed of two distinct subunits: catalytic (C) and regulatory (R). Four regulatory subunits have been identified: RIα, RIβ, RIIα, and RIIβ.These subunits define type I and II cAMP-dependent protein kinases. Following binding of cAMP, the regulatory subunits dissociate from the catalytic subunits, rendering the enzyme active. Type I and type II holoenzymes have three potential C subunits (Cα, Cβ, or Cγ). Type II PKA can be distinguished by autophosphorylation of the R-subunits, while type I PKA binds Mg/ATP with high affinity. Most cells express both type I and type II PKAs. Although the Rα isoforms are ubiquitously expressed, the Rβ isoforms are predominant in nervous and adipose tissues. There are indications that the deletion of the gene for PKA RIIβ results in lack of long-term potentiation in a select group of hippocampal cells, suggesting an important role for this protein in the neurosciences.
Immunofluorescence, Immunoprecipitation, Western Blotting
Spécification
| PKA RIIβ | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG1 | |
| Affinity Purified |
| 45 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Canine, Chicken, Human, Mouse, Rat | |
| Human PKA RIIβ, aa 1-418 | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.