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APH1A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 11643-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16828863

  • 325.38€ / 150µL
Expédition estimée: 30-09-2022
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Description

Description

APH1 is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). The gamma-secretase complex is minimally composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2, although other components may exist. APH1 probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.
Spécification

Spécification

APH1A
Polyclonal
Unconjugated
APH1A
6530402N02Rik, APH 1A, Aph 1alpha, APH1A, CGI 78, Gamma secretase subunit APH 1A, PSF, UNQ579/PRO1141
Rabbit
Antigen Affinity Chromatography
RUO
226548, 365872, 51107
-20°C
Liquid
Western Blot, Immunoprecipitation
0.3 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q8BVF7, Q96BI3
APH1A
APH1A Fusion Protein Ag2238
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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