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APH1A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 11643-1-AP-150UL
Informations supplémentaires : Poids : 0.00010kg
Description
APH1 is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). The gamma-secretase complex is minimally composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2, although other components may exist. APH1 probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.Spécification
| APH1A | |
| Polyclonal | |
| Unconjugated | |
| APH1A | |
| 6530402N02Rik, APH 1A, Aph 1alpha, APH1A, CGI 78, Gamma secretase subunit APH 1A, PSF, UNQ579/PRO1141 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 226548, 365872, 51107 | |
| -20°C | |
| Liquid |
| Immunoprecipitation, Western Blot | |
| 0.3 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q8BVF7, Q96BI3 | |
| APH1A | |
| APH1A Fusion Protein Ag2238 | |
| 150 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |