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Arginase I Mouse, Unlabeled, Clone: 19, BD
Mouse Monoclonal Antibody
330.00€ - 545.00€
Spécification
Antigène | Arginase I |
---|---|
Clone | 19 |
Concentration | 250μg/mL |
Applications | Western Blot |
Classification | Monoclonal |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
---|---|---|---|---|---|---|---|---|---|
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
15855599
|
BD Biosciences
610708 |
50 μg |
330.00€
1 kit |
Expédition estimée: 14-05-2024 Connectez-vous pour voir le stock disponible |
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15865599
|
BD Biosciences
610709 |
150 μg |
545.00€
1 kit |
Expédition estimée: 22-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
Arginase converts arginine into urea plus ornithine, the final step in urea synthesis. Two different isoforms (I&II) have been isolated with approximately 60% homology at the nucleotide level. While type II is present in many tissues, Arginase I is expressed exclusively in liver. In cultured macrophages, as well as in vivo, Arginase I is induced with nitric oxide synthase (NOS) and the arginase I transactivator C/EBPβ in response to lipopolysaccharide. This response occurs in a dose and time-dependent manner. While the mRNA for NOS appears as early as 2h after treatment, mRNA levels for arginase I peak after twelve hours of lipopolysaccharide treatment. Since the synthesis of nitric oxide by NOS requires arginine, the delayed induction of arginase I may be necessary for the regulation of NOS activity.
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Spécification
Arginase I | |
250μg/mL | |
Monoclonal | |
Mouse | |
Cell Biology | |
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
IgG1 | |
Affinity Purified |
19 | |
Western Blot | |
Unconjugated | |
RUO | |
Drosophila, Mouse, Rat | |
Human Arginase I aa. 53-207 | |
Primary | |
Store undiluted at -20°C. |
For Research Use Only.