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ARHGEF7 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

112.71€ - 329.85€

Spécification

Antigène ARHGEF7
Concentration 0.27 mg/mL
Applications Western Blot, Immunocytochemistry, Immunoprecipitation, Immunofluorescence
Conjugué Unconjugated
Format Liquid
Consulter d'autres spécifications

Produits 2
Code produit Marque Quantité Prix Quantité et disponibilité  
Code produit Marque Quantité Prix Quantité et disponibilité  
16802584
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Proteintech
14092-1-AP-150UL
150 μL
329.85€
150µL
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Économisez jusqu'à 
»
Expédition estimée
26-04-2021
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16812584
Afficher les documents
Proteintech
14092-1-AP-20UL
20 μL
112.71€
20µL
Voir les produits de remplacement
Économisez jusqu'à 
»
Expédition estimée
26-04-2021
Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!
Description

Description

The serine/threonine kinase, p21 activated kinase (PAK), is a downstream effector of the small GTPases Cdc42 and Rac. PAK associates with Nck, the p85 and p110 subunits of PI3-kinase and PIX (PAK-interacting exchange factor) in a focal complex. The binding of PIX is necessary for the localization and activation of PAK in the Cdc42 to Rac signaling pathway, and this binding occurs through the high affinity of the N-terminal SH3 domain of PIX for a conserved proline rich PAK sequence. PIX exists as two isoforms, alpha and beta, and both are highly expressed in heart, muscle and thymus tissues of human and rat. alphaPIX is phosphorylated via PDGF and EphB2 receptor signaling pathways or through association with PI3-kinase. The alphaPIX isoform predomitly acts as a guanine nucleotide exchange factor (GEF) on Rac, which may mediate lamellipodia formation.
Spécification

Spécification

ARHGEF7
Western Blot, Immunocytochemistry, Immunoprecipitation, Immunofluorescence
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Polyclonal
-20°C
0.27 mg/mL
Unconjugated
Rabbit
Human, Rat, Mouse
IgG
Antigen Affinity Chromatography
Antibody
FDS