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AXIN1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 16541-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16806204

  • 399.00€ / 150µL
Expédition estimée: 15-04-2024
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Description

Description

Proteintech's AXIN1 antibody 16541-1-AP is a rabbit polyclonal antibody raised against the N-terminus of human AXIN1.

AXIN1 is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a disheveled and axin (DIX) domain and is thought to function as a negative regulator of the WNT signaling pathway that regulates embryonic axis formation. AXIN1 interacts with adenomatosis polyposis coli (APC), beta-catenin, glycogen synthase kinase 3 beta, forming a tetrameric complex resulting in the regulation of the stabilization of beta-catenin. Mutations in the AXIN1 gene have been associated various carcinomas, indicating that it also functions as a tumor suppressor.
Spécification

Spécification

AXIN1
Polyclonal
Unconjugated
AXIN1
AXIN, axin 1, AXIN1, Axis inhibition protein 1, hAxin
Rabbit
Antigen Affinity Chromatography
RUO
8312
-20°C
Liquid
Western Blot
0.16 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O15169
AXIN1
AXIN1 Fusion Protein Ag9858
150 μL
Primary
Human
Antibody
IgG
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