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ACROBiosystems Biotinylated Cynomolgus / Rhesus macaque FcRn Heterodimer Protein, His, Avitag™&Strep II Tag (BLI verified)

Biotinylated Protein

Marque:  ACROBiosystems FCM-C82W5-200UG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15866727

  • 1392.13€ / 200µg
Date d’expédition estimée: 05-01-2022

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Description

Description

FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.

Biotinylated Cynomolgus / Rhesus macaque FcRn Heterodimer Protein, His,Avitag&Strep II Tag (BLI verified), produced by co-expression of FCGRT and B2M, has a calculated MW of 34.1 kDa (FCGRT) and 13.0 kDa (B2M). Subunit FCGRT is fused with an Avi tag (Avit
Spécification

Spécification

NP_001244449.1 (FCGRT) and Q8SPW0.1 (B2M)
HEK293
Cynomolgus / Rhesus macaque
34.1 kDa (FCGRT) and 13.0 kDa (B2M)
200 µg
Ala 24 - Ser 297 (FCGRT) and Ile 21 - Met 119 (B2M)
FcRn,FCGRT and B2M
Precision Avi
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
Powder
>90% as determined by SDS-PAGE
MABSol™ Biotinylated Cynomolgus / Rhesus macaque FcRn Heterodimer Protein, His,Avitag&Strep; II Tag (BLI verified) (FCM-C82W5) is expressed from human HEK293 cells. It contains AA Ala 24 - Ser 297 (FCGRT) and Ile 21 - Met 119 (B2M) (Accession # Q8SPV9-1 (FCGRT) and Q8SPW0-1 (B2M)). In the region Ala 24 - Ser 297 (FCGRT) and Ile 21 - Met 119 (B2M), the AA sequence of Cynomolgus and Rhesus macaque FcRn (FCGRT and B2M) are homologus.
-20°C
FcRn (FCGRT and B2M)
His Tag and Avi Tag and Strep Tag
Vidéos
FDS
Documents
Certificats
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