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ACROBiosystems Biotinylated Human CD3 epsilon Protein, His Tag, ultra sensitivity (primary amine labeling)

Marque:  ACROBiosystems CDE-H8223-25UG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15866397

  • 388.38€ / 25µg
Date d’expédition estimée: 07-01-2022

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Description

Description

CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 12.6 kDa. The protein migrates as 15-16 kDa under reducing (R) condition (SDS-PAGE).
Spécification

Spécification

NP_000724.1
HEK293
Human
12.6 kDa
25 µg
Asp 23 - Asp 126
FLJ18683,T3E,TCRE,CD3E,CD3-epsilon
UltraLys
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
Powder
>90% as determined by reduced SDS-PAGE
MABSol™ Biotinylated Human CD3E, His Tag, primary amine labeling (CDE-H8223) is expressed from human HEK293 cells. It contains AA Asp 23 - Asp 126 (Accession # NP_000724.1). It is the biotinylated form of Human CD3 epsilon Protein (Cat # CDE-H5223).
-20°C
CD3 epsilon
His Tag
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FDS
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