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ACROBiosystems Biotinylated Human CD3 epsilon Protein, His Tag, ultra sensitivity (primary amine labeling)
sur devis
Spécification
| Numéro d’adhésion | NP_000724.1 |
|---|---|
| Poids moléculaire | 12.6 kDa |
| Source | MABSol™ Biotinylated Human CD3E, His Tag, primary amine labeling (CDE-H8223) is expressed from human HEK293 cells. It contains AA Asp 23 - Asp 126 (Accession # NP_000724.1). It is the biotinylated form of Human CD3 epsilon Protein (Cat # CDE-H5223). |
| Immunogène | Asp 23 - Asp 126 |
| Conditions de stockage | -20°C |
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|---|---|---|---|---|---|---|---|---|---|
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
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15856397
|
ACROBiosystems
CDE-H8223-200UG |
200 µg |
Cet article est actuellement indisponible ou discontinu.
Veuillez consulter la page produit pour de possible alternative dans l’onglet |
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|
15866397
|
ACROBiosystems
CDE-H8223-25UG |
25 µg |
Cet article est actuellement indisponible ou discontinu.
Veuillez consulter la page produit pour de possible alternative dans l’onglet |
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Description
CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 12.6 kDa. The protein migrates as 15-16 kDa under reducing (R) condition (SDS-PAGE).Spécification
| NP_000724.1 | |
| MABSol™ Biotinylated Human CD3E, His Tag, primary amine labeling (CDE-H8223) is expressed from human HEK293 cells. It contains AA Asp 23 - Asp 126 (Accession # NP_000724.1). It is the biotinylated form of Human CD3 epsilon Protein (Cat # CDE-H5223). | |
| -20°C | |
| CD3 epsilon | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| MABSol™ Biotin Labeled Proteins |
| 12.6 kDa | |
| Asp 23 - Asp 126 | |
| FLJ18683,T3E,TCRE,CD3E,CD3-epsilon | |
| UltraLys | |
| His Tag | |
| Less than 1.0 EU / µg by the LAL method. | |
| Powder | |
| >90% as determined by reduced SDS-PAGE |