missing translation for 'onlineSavingsMsg'
Learn More

ACROBiosystems Biotinylated Human ROR1 Protein, Fc, Avitag™

Biotinylated Protein

Marque:  ACROBiosystems RO1-H82F4-25UG

Informations supplémentaires : Poids : 0.00001kg

 Afficher plus de versions de ce produit

Code produit. 15867597

  • 353.08€ / 25µg
Date d’expédition estimée: 05-01-2022

Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!


Description

Description

Tyrosine-protein kinase transmembrane receptor ROR1 is also known as Neurotrophic tyrosine kinase, receptor-related 1 (NTRKR1), which belongs to the protein kinase superfamily or tyr protein kinase family or ROR subfamily. ROR1 contains 1 FZ (frizzled) domain, 1 Ig-like C2-type (immunoglobulin-like) domain, 1 kringle domain, 1 protein kinase domain. ROR1 is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. ROR1 could interact with casein kinase 1 epsilon (CK1ε) to activate phosphoinositide 3-kinase-mediated AKT phosphorylation and cAMP-response-element-binding protein (CREB), which was associated with enhanced tumor-cell growth.

This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 70.1 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

AAA60275.1
HEK293
Human
70.1 kDa
25 µg
Gln 30 - Glu 403
ROR1,NTRKR1
Precision Avi
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
Powder
>95% as determined by SDS-PAGE
Biotinylated Human ROR1, Fc,Avitag (RO1-H82F4) is expressed from human 293 cells (HEK293). It contains AA Gln 30 - Glu 403 (Accession # Q01973-1).
-20°C
ROR1
Fc Tag and Avi Tag
Vidéos
FDS
Documents
Certificats
Promotions

Promotions