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ACROBiosystems Biotinylated Human ROR1 Protein, Fc, Avitag™
Biotinylated Protein
423.38€ - 1862.87€
Spécification
Numéro d’adhésion | AAA60275.1 |
---|---|
Poids moléculaire | 70.1 kDa |
Source | Biotinylated Human ROR1, Fc,Avitag (RO1-H82F4) is expressed from human 293 cells (HEK293). It contains AA Gln 30 - Glu 403 (Accession # Q01973-1). |
Immunogène | Gln 30 - Glu 403 |
Conditions de stockage | -20°C |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
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Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
15867597
|
ACROBiosystems
RO1-H82F4-25UG |
25 μg |
423.38€
25µg |
Expédition estimée: 30-04-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
15857597
|
ACROBiosystems
RO1-H82F4-200UG |
200 μg |
1862.87€
200µg |
Expédition estimée: 30-04-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
Tyrosine-protein kinase transmembrane receptor ROR1 is also known as Neurotrophic tyrosine kinase, receptor-related 1 (NTRKR1), which belongs to the protein kinase superfamily or tyr protein kinase family or ROR subfamily. ROR1 contains 1 FZ (frizzled) domain, 1 Ig-like C2-type (immunoglobulin-like) domain, 1 kringle domain, 1 protein kinase domain. ROR1 is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. ROR1 could interact with casein kinase 1 epsilon (CK1ε) to activate phosphoinositide 3-kinase-mediated AKT phosphorylation and cAMP-response-element-binding protein (CREB), which was associated with enhanced tumor-cell growth.
This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 70.1 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spécification
AAA60275.1 | |
Biotinylated Human ROR1, Fc,Avitag (RO1-H82F4) is expressed from human 293 cells (HEK293). It contains AA Gln 30 - Glu 403 (Accession # Q01973-1). | |
-20°C | |
ROR1 | |
Human | |
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5 | |
HEK293 | |
MABSol™ Biotin Labeled Proteins |
70.1 kDa | |
Gln 30 - Glu 403 | |
ROR1,NTRKR1 | |
Precision Avi | |
Fc Tag and Avi Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |