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ACROBiosystems Biotinylated Human TFPI Protein, His Tag, ultra sensitivity (primary amine labeling)

Marque:  ACROBiosystems TFI-H8226-25UG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15867747

  • 292.55€ / 25µg
Date d’expédition estimée: 07-01-2022

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Description

Description

Tissue factor pathway inhibitor (TFPI) is also known as Extrinsic pathway inhibitor (EPI), Lipoprotein - associated coagulation inhibitor (LACI), is a plasma proteinase inhibitor synthesized by vascular endothelial cells and part of it is associated with glycosaminoglycans of these cells. TFPI is a single-chain polypeptide which can reversibly inhibit Factor Xa (Xa) and Thrombin (Factor IIa). TFPI is a secreted protein with a N­terminal acidic region, three Kunitz (K) domains separated with by two linker regions, and a C­terminal basic region. The first K domain inhibits coagulation factor VIIa complexed to tissue factor (TF); The second K domain inhibits factor Xa; The third K domain binds to heparin; The C­terminal basic region may have several functions. For example, it plays an important role in binding of TFPI to cell surfaces.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 30.0 kDa. The protein migrates as 41-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

NP_006278.1
HEK293
Human
30.0 kDa
25 µg
Asp 29 - Lys 282
TFPI,LACI,TFPI1,EPI,TFI
UltraLys
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
Powder
>90% as determined by SDS-PAGE
MABSol™ Biotinylated Human TFPI, His Tag, primary amine labeling (TFI-H8226) is expressed from human HEK293 cells. It contains AA Asp 29 - Lys 282 (Accession # NP_006278.1). It is the biotinylated form of Human TFPI, His Tag (TFI-H5226).
-20°C
TFPI
His Tag
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FDS
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