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CaMKIV Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 13263-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16801394

  • 112.71€ / 20µL

Expédition estimée
02-03-2021

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Description

Description

CaM kinase IV (CaMKIV), in a calcium and calmodulin dependent manner, is implicated in phosphorylating numerous transcription factors including the CCAAT enhancer binding protein (C/EBP), serum response factor (SRF), and cyclic AMP response element binding protein (CBP). The nuclear localization of this protein is consistent with its role in mediating calcium-dependent gene expression. CaMKIV is particularly abundant in testis, T-cells, and neurons but is also found in other tissues to varying degrees. In neurons, CaMKIV is thought to play an important role in synaptic plasticity via its gene regulatory effects. In T-cells, this protein plays an important role in calcium signaling which could affect the transcription regulatory protein, nuclear factor of activated T-cells (NFAT). CaMKIV is encoded, along with calspermin, by the CaMKIV gene. It has been found that, in testes, CaMKIV is expressed in germ cells and found to be associated with chromatin. The association of CaMKIV with chromatin suggests a potential role in chromatin remodeling during nuclear condensation in spermatids.
Spécification

Spécification

CaMKIV
0.3 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P08414, P13234, Q16566
CaM kinase GR, CaMK GR, CAMK4, CaMKIV
Rabbit
IgG
20 μL
-20°C
Primary
12326, 25050, 814
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
CAMK4
Liquid
CAMK4
CaMKIV Fusion Protein Ag3922
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Rat, Mouse, Human
Vidéos
FDS
Documents