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CD123 Monoclonal Antibody (6H6), Super Bright™ 645, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Marque:  Affymetrix eBioscience 64-1239-42

Informations supplémentaires : Poids : 0.01000kg

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Code produit. 15875673

  • 377.00€ / 100 pièces
Expédition estimée: 06-05-2024
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Description

Description

Description: The A7R34 monoclonal antibody reacts with mouse CD127, the high affinity alpha subunit of the mouse IL-7 receptor. IL-7 receptor alpha chain is expressed by immature B cells in the bone marrow, double-negative (CD4-CD8-), single-positive (CD4+ and CD8+), but not double-positive (CD4+CD8+) thymocytes. In the periphery, mature T cells express CD127 at low level. A7R34 inhibits binding of IL-7 to its receptor and has been used in in vivo and in vitro studies to elucidate the role of IL-7 in T and B cell development and activation. Binding of A7R34 blocks the binding of SB/199, another antibody which recognizes mouse CD127. Applications Reported: This A7R34 antibody has been reported for use in flow cytometric analysis. Applications Tested: This A7R34 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Super Bright 645 is a tandem dye that can be excited with the violet laser line (405 nm) and emits at 645 nm. We recommend using a 660/20 bandpass filter. Please make sure that your instrument is capable of detecting this fluorochrome.

CD123 Monoclonal antibody specifically detects CD123 in Human samples. It is validated for Flow Cytometry.
Spécification

Spécification

CD123
Monoclonal
5 μL/Test
PBS with BSA and 0.09% sodium azide; pH 7.2
P26951
IL3RA
Affinity chromatography
RUO
3563
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
6H6
Super Bright 645
IL3RA
CD123; CD123 antigen; CDw123; Cyrl; cytokine receptor-like protein CYRL; hIL-3Ra; Il-3 alpha subunit; IL-3 receptor alpha chain; IL-3 receptor alpha SP2 isoform; IL-3 receptor subunit alpha; IL3R; IL-3R subunit alpha; Il3ra; IL-3RA; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; interleukin 3 receptor subunit alpha; interleukin 3 receptor, alpha; interleukin 3 receptor, alpha (low affinity); interleukin 3 receptor, alpha chain; interleukin-3 receptor class II alpha chain; Interleukin-3 receptor subunit alpha; Sut-1
Mouse
100 Tests
Primary
Human
Antibody
IgG1 κ
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