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CD127 Monoclonal Antibody (eBioRDR5), Alexa Fluor™ 488, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

131.00€ - 326.00€

Spécification

Antigène CD127
Clone eBioRDR5
Applications Flow Cytometry
Classification Monoclonal
Conjugué Alexa Fluor 488
Consulter d'autres spécifications

Produits 2
Code produit Marque Quantité Prix Quantité et disponibilité  
Code produit Marque Quantité Prix Quantité et disponibilité  
16370974
Afficher les documents Détails de la promotion
Affymetrix eBioscience
53-1278-42
100 Tests
326.00€
100 pièces
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Expédition estimée: 22-04-2024
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16360974
Afficher les documents Détails de la promotion
Affymetrix eBioscience
53-1278-41
25 Tests Cet article est actuellement indisponible ou discontinu. Veuillez consulter la page produit pour de possible alternative dans l’onglet
N/A Voir les produits de remplacement
Économisez jusqu'à 
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Description

Description

Description: The eBioRDR5 monoclonal antibody reacts with human CD127 (Interleukin-7 Receptor alpha). CD127 complexes with CD132, also known as the common gamma chain (gamma c), to form the multi-functional IL-7 receptor (IL-7R). CD127 is a type I glycoprotein with a molecular weight of 75-80 kDa and is expressed by immature B cells through the early pre-B stage, by thymocytes during several stages of their development, and on most mature T cells, with transient down-regulation upon activation. Binding of IL-7 results in signal transduction which occurs through several tyrosine kinase pathways including the Jak/STAT pathway. IL-7 is indispensible for the development of lymphocytes, and the control of homeostatic proliferation of T-cells in the periphery. In addition, IL-7R signaling is know to be involved in the regulation of T cell receptor (TCR) locus rearrangement in gamma delta T cells. Interestingly, recently it has been demonstrated that CD127 expression is down-regulated on CD4+CD25+ regulatory T cells (T regs). While the co-expression of CD4 and CD25 has become widely used as an indicator of T regs, this method of identification may also include cells without suppressive activity.

CD127 Monoclonal antibody specifically detects CD127 in Human samples. It is validated for Flow Cytometry.
Spécification

Spécification

CD127
Flow Cytometry
Alexa Fluor 488
Mouse
Human
3575
Primary
4° C, store in dark, DO NOT FREEZE!
eBioRDR5
Monoclonal
Liquid
RUO
P16871
IgG1 κ
Affinity chromatography
Antibody
Vidéos
FDS
Documents

Documents

Product Certifications