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CD127 Mouse, anti-Human, R718, Clone: HIL-7R-M21, BD Horizon™
Mouse Monoclonal Antibody
246.00€ - 488.00€
Spécification
| Antigène | CD127 |
|---|---|
| Clone | HIL-7R-M21 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Conjugué | R718 |
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|---|---|---|---|---|---|---|---|---|---|
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|
17277754
|
BD Biosciences
566968 |
25 Tests |
246.00€
25 tests |
Expédition estimée: 15-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
|
17267754
|
BD Biosciences
566967 |
100 Tests |
488.00€
100 tests |
Expédition estimée: 15-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
The hIL-7R-M21 monoclonal antibody specifically binds to the 60-90 kDa glycoprotein, CD127. CD127 is also known as the IL-7 receptor alpha (IL-7Rα) subunit. The IL-7 receptor complex is a heterodimer composed of CD127 and the common gamma chain (γc, CD132), shared by other cytokine receptors (IL-2R, IL-4R, IL-9R, IL-15R, and IL-21R). CD127 is expressed on thymocytes, T- and B-cell progenitors, mature T cells, and some lymphoid and myeloid cells. In vitro experiments show the expression of CD127 is down-regulated following T cell activation. Studies indicate that the IL-7 Receptor plays an important role in the proliferation and differentiation of mature T cells. Recently, it has been shown that low surface expression of CD127, in combination with intermediate to high surface expression of CD25, the α chain of the IL-2 receptor complex, can distinguish between human regulatory and conventional CD4+ T cells in human adult and cord blood, lymph nodes and thymus.
Spécification
| CD127 | |
| Flow Cytometry | |
| R718 | |
| Mouse | |
| Human | |
| Refrigerate Upon Arrival |
| HIL-7R-M21 | |
| Monoclonal | |
| Liquid | |
| RUO | |
| Primary |