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CD152 Mouse anti-Human, PE-Cy5, Clone: BNI3, BD
Mouse Monoclonal Antibody
228.00€ - 477.00€
Spécification
| Antigène | CD152 |
|---|---|
| Clone | BNI3 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Conjugué | PE-Cyanine5 |
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|---|---|---|---|---|---|---|---|---|---|
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|
15821269
|
BD Biosciences
561717 |
25 Tests |
228.00€
1 pièce |
Expédition estimée: 16-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
|
15878488
|
BD Biosciences
555854 |
100 Tests |
477.00€
1 pièce |
Expédition estimée: 16-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
The BNI3 monoclonal antibody specifically binds to the human cytolytic T lymphocyte-associated antigen, CTLA-4. CTLA-4 is transiently expressed on activated CD28+ T cells and binds to CD80 and CD86 present on antigen presenting cells (APC) with high avidity. This interaction appears to deliver a negative regulatory signal to the T cell. There are recent reports that indicate that CTLA-4 is also expressed on B cells when cultured with activated T cells, suggesting a possible role of CTLA-4 in the regulation of B-cell response. Immobilized BNI3.1 antibody enhances T-cell proliferation induced by antibody-mediated crosslinking of CD3 and CD28. Recent studies have shown that CD152 can be expressed by regulatory T (Treg) cells. After cellular fixation and permeabilization, the BNI3 antibody can stain intracellular CD152 expressed in T cells including Treg cells. Clone BNI3.1 was studied in the VI Leukocyte Typing Workshop.
Spécification
| CD152 | |
| Flow Cytometry | |
| PE-Cyanine5 | |
| RUO | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| IgG2a κ | |
| Affinity Purified | |
| CTLA-4; AILIM; Cytotoxic T-lymphocyte protein 4 |
| BNI3 | |
| Monoclonal | |
| Mouse | |
| Human | |
| Human CTLA4 Recombinant Protein | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
For Research Use Only.