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CD154 (CD40 Ligand) Mouse anti-Cynomolgus Monkey, Human, Alexa Fluor 700, Clone: 24-31, Invitrogen™

Mouse Monoclonal Antibody

Marque:  Affymetrix eBioscience 56-1548-42

Informations supplémentaires : Poids : 0.01000kg

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Code produit. 16626444

  • 232.00€ / 100 tests

Date d’expédition estimée: 27-10-2021

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Description

Description

Description: The 24-31 monoclonal antibody reacts with human CD154, a 39 kDa transmembrane glycoprotein also known as gp39 and CD40 ligand (CD40L). CD154 is a member of the TNF superfamily and is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells including B cells, monocytes/macrophages and dendritic cells, CD154 serves a crucial function in T-APC cognate interaction. CD154 interaction with CD40 transduces signals for T-dependent B-cell activation and induces B cell cycle entry. 24-31 cross-reacts with the Cynomolgus monkey CD154. Applications Reported: This 24-31 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 24-31 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Alexa Fluor 700 emits at 723 nm and can be excited with the red laser (633-647 nm). Most instruments will require a 685 LP mirror and 710/20 band pass filter. Please make sure that your instrument is capable of detecting this fluorochrome. Excitation: 633-647 nm; Emission: 723 nm; Laser: Red Laser

CD40 Ligand (CD40-L), or CD154, is a membrane glycoprotein and differentiation antigen expressed on the surface of T cells. The CD40 Ligand stimulates B cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 Ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL-2.
Spécification

Spécification

CD154 (CD40 Ligand)
24-31
Alexa Fluor 700
CD40LG
Liquid
CD40LG
IgG1, kappa
100 Tests
4°C, store in dark, DO NOT FREEZE!
Primary
102138630, 959
Flow Cytometry
5 μL/Test
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
P29965
CD154; CD40 antigen ligand; CD40 ligand; CD40 ligand CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; CD40L; CD40-L; Cd40lg; gp39; hCD40L; H-CD-40-L; HIGM1; IGM; IMD3; Ly62; Ly-62; M-CD-40-L; RP23-153G22.3; T-B cell-activating molecule; T-BAM; T-cell antigen Gp39; TNF-related activation protein; Tnfsf5; TRAP; tumor necrosis factor (ligand) superfamily member 5; tumor necrosis factor (ligand) superfamily, member 5; Tumor necrosis factor ligand superfamily member 5
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Cynomolgus Monkey, Human
Vidéos
FDS
Documents
Certificats