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CD161 Mouse anti-Human, APC, Clone: DX12, BD
Mouse Monoclonal Antibody
280.00€ - 540.00€
Spécification
| Antigène | CD161 |
|---|---|
| Clone | DX12 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Conjugué | APC |
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|---|---|---|---|---|---|---|---|---|---|
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|
15841279
|
BD Biosciences
561729 |
25 Tests |
280.00€
1 pièce |
Expédition estimée: 03-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
|
15876448
|
BD Biosciences
550968 |
100 Tests |
540.00€
1 pièce |
Expédition estimée: 03-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
The DX12 monoclonal antibody specifically binds to human CD161 which is also known as Natural killer cell surface protein P1A (NKR-P1A). CD161 is encoded by the KLRB1 (Killer cell lectin-like receptor subfamily B member 1) gene. CD161 is a member of the C-type lectin superfamily and is also referred to as C-type lectin domain family 5 member B (CLEC5B). CD161 is a 80 kDa disulfide-linked homodimer, type II membrane glycoprotein. CD161 is expressed mostly on NK cell populations and on subsets of CD4+ and CD8+ αβ T cells, NKT cells and γδ T cells. Reports indicate that CD161 is expressed preferentially on CD45RO+ T cells, however, it can be found on a subset of thymocytes and fetal liver T cells. Its function has not been fully elucidated, but reports indicate that NKR-P1A may serve as a specific receptor for some NK cell targets. The DX12 antibody can reportedly inhibit spontaneous cytotoxicity mediated by certain NK cell clones.
Spécification
| CD161 | |
| Flow Cytometry | |
| APC | |
| RUO | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| IgG1 κ | |
| Affinity Purified |
| DX12 | |
| Monoclonal | |
| Mouse | |
| Human | |
| Human NKR-P1A Transfected Mouse Fibroblasts | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
For Research Use Only.