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CD162 (PSGL-1) Rat anti-Mouse, Alexa Fluor 488, Clone: 4RA10, Invitrogen™

Rat Monoclonal Antibody

Marque:  Affymetrix eBioscience 53-1621-82

Informations supplémentaires : Poids : 0.01000kg

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Code produit. 16626404

  • 359.00€ / 1 pièce

Date d’expédition estimée: 27-10-2021

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Description

Description

Description: This 4RA10 monoclonal antibody reacts with mouse CD162, which is also known as P-selectin glycoprotein ligand-1 (PSGL-1). This clone has been successfully used in flow cytometry and has been reported to block binding of CD162 to CD62P and CD62L. Applications Reported: This 4RA10 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 4RA10 antibody has been tested by flow cytometric analysis of mouse splenocytes. This may be used at less than or equal to 0.06 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser

CD162 (PSGL-1) is a 120 kDa homodimer protein found on the surface of leukocytes and platelets. CD162 is known to bind CD62P (P-selectin), CD62L (L-selectin), and to a lower degree CD62E (E-selectin). These interactions play a critical role in leukocyte adhesion, rolling and extravasation. CD162 has been shown to be an important immune marker of T cell exhaustion in chronic viral infections and cancer.
Spécification

Spécification

CD162 (PSGL-1)
4RA10
Alexa Fluor 488
SELPLG
Liquid
SELPLG
Mouse PSGL-1 human IgG1 fusion protein
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q62170
CD162; CLA; cutaneous lymphocyte-associated associated antigen; leukocyte cell surface adhesion molecule; P-selectin glycoprotein ligand 1; P-selectin glycoprotein ligand 1 propeptide; P-selectin glycoprotein ligand-1; Psgl1; PSGL-1; Selectin P ligand; selectin, platelet (p-selectin) ligand; Selp1; SELPG; Selpl; SELPLG
Rat
IgG1, kappa
100 μg
4°C, store in dark, DO NOT FREEZE!
Primary
20345
Vidéos
FDS
Documents
Certificats