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CD193 (CCR3) Mouse anti-Human, Alexa Fluor 700, Clone: eBio5E8-G9-B4 (5E8-G9-B4), eBioscience™ Invitrogen™

Mouse Monoclonal Antibody

Marque:  Invitrogen 56-1939-41

Informations supplémentaires : Poids : 0.01000kg

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Code produit. 16636444

  • 220.00€ / 25 pièces

Date d’expédition estimée: 29-10-2021

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Description

Description

The eBio5E8-G9-B4 MAb reacts with human CD193 (CCR3, CKR3). CD193 is a member of the seven transmembrane G-protein coupled receptor (GPCR) family, and is a high affinity chemokine receptor for the chemokines eotaxin-1 (CCL11), eotaxin-2 (CCL24), eotaxin-3 (CCL26) and MCP-4 (CCL13), but has also been reported to bind RANTES, MCP-3 and MCP-4. CD193 is highly expressed on the surface of eosinophils, and is the key eosinophil chemokine receptor responsible for the regulation of eosinophil migration and function. In addition to eosinophils, CD193 is also expressed on CD4+ TH2 cells, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitors and airway epithelial cells. CD193 likely plays an important role in the migration of eosinophils in allergic airway inflammation and asthma. CD193 can also serve as a receptor for HIV-1 cell entry.

CD193 (CCR3) Monoclonal antibody specifically detects CD193 (CCR3) in Human samples. It is validated for Flow Cytometry
Spécification

Spécification

CD193 (CCR3)
Flow Cytometry
eBio5E8-G9-B4 (5E8-G9-B4)
Alexa Fluor 700
CCR3
b-chemokine receptor; CC chemokine receptor 3; C-C chemokine receptor type 3; C-C CKR-3; C-C motif chemokine receptor 3; CC-CKR3; CC-CKR-3; CCR3; CCR-3; CD193; chemokine (C-C motif) receptor 3; chemokine (C-C) receptor 1,-like 2; chemokine (C-C) receptor 3; CKR3; Cmkbr1l2; CMKBR3; eosinophil CC chemokine receptor 3; eosinophil eotaxin receptor; Macrophage inflammatory protein 1-alpha receptor-like 2; MGC102841; MIP-1 alpha RL2; MIP-1 alphaRL2; Probable C-C chemokine receptor type 3
IgG2b, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
1232
Liquid
Monoclonal
5 μL/Test
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
P51677
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Vidéos
FDS
Documents
Certificats