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CD200R3 Monoclonal Antibody (Ba13), PE, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

156.00€ - 373.00€

Spécification

Antigène CD200R3
Clone Ba13
Concentration 0.2 mg/mL
Applications Flow Cytometry
Classification Monoclonal
Consulter d'autres spécifications

Produits 2
Code produit Marque Quantité Prix Quantité et disponibilité  
Code produit Marque Quantité Prix Quantité et disponibilité  
16636274
Afficher les documents Détails de la promotion
Affymetrix eBioscience
12-2001-82
100 μg
373.00€
1 pièce
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Expédition estimée: 16-04-2024
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16626274
Afficher les documents Détails de la promotion
Affymetrix eBioscience
12-2001-80
25 μg Cet article est actuellement indisponible ou discontinu. Veuillez consulter la page produit pour de possible alternative dans l’onglet
N/A Voir les produits de remplacement
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Description

Description

Description: This Ba13 monoclonal antibody recognizes mouse CD200R3, a surface receptor expressed by basophils and mast cells. Applications Reported: This Ba13 antibody has been reported for use in flow cytometric analysis. Applications Tested: This Ba13 antibody has been tested by flow cytometric analysis of MC/9 cell line. This may be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.

CD200R3 is a dimeric cell surface receptor also known as CD200RLb. CD200R3 contains two Ig-like extracellular domains and as such is a member of the immunoglobulin superfamily of receptors. The intracellular region of CD200R3 associates with the adaptor molecule DAP12, and possibly also DAP10, CD3 zeta and FcR gamma-chain, indicating that it is capable of transducing stimulatory signals. In this respect CD200R3 bears similarity to activatory receptors CD200R2 and CD200R4. In contrast, an inhibitory receptor CD200R (also known as CD200R1) relies on other adaptors. CD200R3 is primarily expressed by basophils and mast cells, cells known to be involved in anti-parasitic immune responses and frequently also allergic reactions. The surface expression of CD200R3 decreases when basophils are activated by ligating their CD16 and CD32. Remarkably, most of this downregulation is observed within the first 30 minutes after activation. Unlike CD200R, CD200R3 does not bind CD200.
Spécification

Spécification

CD200R3
0.2 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
74603
Mouse primary basophils
Primary
Antibody
Ba13
Flow Cytometry
PE
Rat
Mouse
Q5UKY4
CD200R3
IgG2a κ
Affinity chromatography
CD200R3
Vidéos
FDS
Documents

Documents

Product Certifications