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CD204 Monoclonal Antibody (PSL204), PE-Cyanine7, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

185.00€ - 446.00€

Spécification

Antigène CD204
Clone PSL204
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
Consulter d'autres spécifications

Produits 2
Code produit Marque Quantité Prix Quantité et disponibilité  
Code produit Marque Quantité Prix Quantité et disponibilité  
15702476
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Affymetrix eBioscience
25-2045-42
100 Tests
446.00€
100 pièces
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Expédition estimée: 14-05-2024
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15792466
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Affymetrix eBioscience
25-2045-41
25 Tests Cet article est actuellement indisponible ou discontinu. Veuillez consulter la page produit pour de possible alternative dans l’onglet
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Description

Description

This monoclonal antibody PSL204 reacts with human CD204, also known as Macrophage Scavenger Receptor 1 (MSR1), Scavenger Receptor Type A (SR-A), or SCARA1. It is expressed by multiple populations of macrophages and dendritic cells. CD204 belongs to the class A family of scavenger receptors, a group of five homotrimetric transmembrane proteins that contain a short cytoplasmic tail and extracellular C -terminus. Other members of this family include: MARCO (SCARA2), CSR (SCARA3), SRCL (SCARA4) and SCARA5. CD204 binds and internalizes oxidized low density lipoproteins (LDL), which drives macrophage differentiation into foam cells, secretion of inflammatory cytokines, and development of atherosclerotic lesions. In addition to oxidized LDL, CD204 binds and uptakes a wide variety of macromolecules, including bacterial cell wall components, viral DNA, calciprotein complexes, apoptotic cells, and beta-amyloid fibrils. This broad binding specificity implicates CD204-expressing macrophages in a number of physiological processes and pathologies, such as host defense, inflammation, bone remodeling, atherosclerosis, sepsis, and Alzheimer's disease. In humans, CD204 exists as 3 splice variants. The more ubiquitous full length isoform (type I, SR-AI), a shorter isoform (type II, SR-AII) that lacks the C-terminal cysteine-rich domain, and the shortest isoform (type III, SR-AIII).

CD204 Monoclonal antibody specifically detects CD204 in Human samples. It is validated for Flow Cytometry.
Spécification

Spécification

CD204
5 μL/Test
Monoclonal
Liquid
RUO
P21757
MSR1
Primary
4° C, store in dark, DO NOT FREEZE!
MSR1
PSL204
Flow Cytometry
PE-Cyanine7
Mouse
Human
4481
IgG1 κ
Affinity chromatography
Antibody
Vidéos
FDS
Documents

Documents

Product Certifications

For Research Use Only