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CD21 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
140.00€ - 399.00€
Spécification
Antigène | CD21 |
---|---|
Concentration | 0.13 mg/mL |
Applications | Immunohistochemistry (Paraffin) |
Classification | Polyclonal |
Conjugué | Unconjugated |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
---|---|---|---|---|---|---|---|---|---|
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
16842845
|
Proteintech
24374-1-AP-20UL |
20 μL |
140.00€
20µL |
Expédition estimée: 06-05-2024 Connectez-vous pour voir le stock disponible |
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16832845
|
Proteintech
24374-1-AP-150UL |
150 μL |
399.00€
150µL |
Expédition estimée: 06-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
CD21 (complement receptor 2, CR2, C3D receptor, EBV receptor) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintece of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to follicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands. CD21 functions as receptor for C3d, C3dg and iC3b complement components, for EBV and for IFN alpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation. Genetic variations in the CD21 gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively, spliced transcript variants encoding different isoforms of CD21 have been found.Spécification
CD21 | |
Immunohistochemistry (Paraffin) | |
Unconjugated | |
Rabbit | |
Human | |
P20023 | |
1380 | |
CD21 Fusion Protein Ag18058 | |
Primary | |
-20°C | |
CR2 |
0.13 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
C3DR, CD21, Complement C3d receptor, Complement receptor type 2, CR2, EBV receptor, Epstein Barr virus receptor, SLEB9 | |
CR2 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |