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CD22 Mouse anti-Human, APC, Clone: eBio4KB128 (4KB128), eBioscience™ Invitrogen™

Mouse Monoclonal Antibody

Marque:  Invitrogen 17-0229-42

Informations supplémentaires : Poids : 0.01000kg

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Code produit. 16636304

  • 396.00€ / 100 pièces

Date d’expédition estimée: 05-11-2021

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Description

Description

The eBio4KB128 monoclonal antibody recognizes human CD22 (Siglec-2), which is a member of the siglec subgroup of the Ig superfamily. CD22 is a type I transmembrane glycoprotein composed of two polypeptide chains, CD22 alpha and CD22 beta, of 130 and 140 kDa respectively, produced by alternative splicing of the CD22 gene. CD22 is expressed at high levels on mature B cells and B cell lymphomas. The extracellular portion of CD22 contains seven Ig-like domains, some of which are capable of binding ligands with sialic acid moieties expressed on epithelial, endothelial, B and T cells. The intracellular portion of CD22 contains 6 tyrosine residues contained within immunotyrosine-based inhibitory motifs (ITIM) and immunotyrosine-based activation-like motifs, which are phosphorylated upon B-cell receptor engagement, which enables CD22 to participate in the positive and negative regulation of B-cell receptor signaling. Applications Reported: This eBio4KB128 (4KB128) antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBio4KB128 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5 μL (0.125 μg) per test. A test is defined as the amount ( μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser

CD22 Monoclonal antibody specifically detects CD22 in Human samples. It is validated for Flow Cytometry
Spécification

Spécification

CD22
Flow Cytometry
eBio4KB128 (4KB128)
APC
CD22
A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; Cd22; CD22 antigen; CD22 molecule; FLJ22814; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Siglec2; SIGLEC-2; T-cell surface antigen Leu-14
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
933
Liquid
Monoclonal
5 μL/Test
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
P20273
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Vidéos
FDS
Documents
Certificats