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Invitrogen™ CD229 Monoclonal Antibody (HLy9.25)
Mouse Monoclonal Antibody
Marque: Invitrogen™ MA110149
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Description
This antibody recognizes an extracellular epitope of CD229 / Ly9, a 100-120 kDa cell surface glycoprotein expressed on T and B cells.
CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.
Spécification
| CD229 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 15mM sodium azide; pH 7.4 | |
| Q9HBG7 | |
| Ly9 | |
| CD299-transfected 300.19 pre-B cell line. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Flow Cytometry, Immunoprecipitation, Western Blot, Immunocytochemistry | |
| HLy9.25 | |
| Unconjugated | |
| Ly9 | |
| AI893573; CD229; CDABP0070; Cell surface molecule Ly-9; hly9; Lgp100; LY9; Ly-9; Lymphocyte antigen 9; mLY9; RP11-312J18.1; Signaling lymphocytic activation molecule 3; SLAM family member 3; SLAMF3; T100; T-lymphocyte surface antigen Ly-9 | |
| Mouse | |
| Protein A | |
| RUO | |
| 4063 | |
| 4°C, do not freeze | |
| Liquid |
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