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CD3 Mouse anti-Human, Brilliant Ultraviolet 737, Clone: SK7, BD Horizon™

Mouse Monoclonal Antibody

Marque:  BD Biosciences 612752

Informations supplémentaires : Poids : 0.00060kg

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Code produit. 17267854

  • 770.00€ / 100 tests
Expédition estimée: 02-01-2023
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Description

Description

The SK7 (Leu-4) monoclonal antibody specifically binds to the epsilon chain of the CD3 antigen/T-cell antigen receptor (TCR) complex. This complex is composed of at least six proteins that range in molecular weight from 20 to 30 kDa. The antigen recognized by CD3 antibodies is noncovalently associated with either α / β or γ/ δ TCR (70 to 90 kDa). The CD3 antigen is present on 61% to 85% of normal peripheral blood lymphocytes 60% to 85% of thymocytes and on Purkinje cells in the cerebellum. The soluble form of this antibody has a mitogenic effect on most peripheral blood T lymphocytes, provided appropriate functional monocytes are present.

Due to spectral differences between labeled cells and beads, using BD™ CompBeads can result in incorrect spillover values when used with BD Horizon BUV737 reagents. Therefore, the use of BD CompBeads or BD CompBeads Plus to determine spillover values for these reagents is not recommended. Different BUV737 reagents (e.g., CD4 vs. CD45) can have slightly different fluorescence spillover therefore, it may also be necessary to use clone specific compensation controls when using these reagents.

Spécification

Spécification

CD3
Monoclonal
Brilliant Ultraviolet 737
Mouse
Affinity Purified
RUO
Human
IgG1 κ
Flow Cytometry
SK7
Aqueous buffered solution containing ≤0.09% sodium azide.
Human Thymocytes
100 Tests
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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