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CD32 Mouse anti-Human, Biotin, Clone: 6C4 (CD32), Invitrogen™

Mouse Monoclonal Antibody

Marque:  Affymetrix eBioscience 13-0329-80

Informations supplémentaires : Poids : 0.01000kg

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Code produit. 16646284

  • 143.00€ / 2 pièces

Date d’expédition estimée: 04-11-2021

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Description

Description

Description: This 6C4 monoclonal antibody reacts with human CD32 (also known as Fc gammaRII). This antibody recognizes two isoforms of the receptor, Fc gammaRIIA and Fc gammaRIIB. These 40-kDa polymorphic transmembrane glycoproteins are expressed on B cells, granulocytes, monocytes, macrophages, and platelets. Moreover, these receptors are detected on natural killer cells. CD32 enables interaction between Fc gammaRII-expressing cells and opsonized antigen or IgG-containing immune complexes. Both receptors exhibit low affinity towards IgG and play a role in inflammation and autoimmune disease. This clone has been reported to inhibit Ig binding in a rosette blocking assay. Applications Reported: This 6C4 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 6C4 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
Spécification

Spécification

CD32
6C4 (CD32)
Biotin
FCGR2B
Liquid
FCGR2A, FCGR2B, FCGR2C
IgG1, kappa
25 μg
4°C, do not freeze
Primary
2212, 2213, 9103
Flow Cytometry
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P12318, P31994, P31995
BOS_2622; BOS_2675; CD32; CD32 receptor 2; CD32 receptor 2a; CD32A; CD32B; CD32C; CDw32; Fc fragment of IgG receptor IIa; Fc fragment of IgG receptor IIb; Fc fragment of IgG receptor IIc (gene/pseudogene); Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc fragment of IgG, low affinity IIc, receptor for (CD32); Fc gamma receptor II; Fc gamma receptor IIa; Fc gamma receptor IIb; Fc gamma receptor IIC; Fc gamma RIIb; FCG2; Fc-gamma RII; Fc-gamma RII-a; Fc-gamma RII-b; Fc-gamma RII-c; Fc-gamma-RIIa; Fc-gamma-RIIb; Fc-gamma-RIIc; Fc-gamma-RII-D; FcGR; FCGR2; FCGR2A; FCGR2A1; FCGR2B; FCGR2C; FcRII; fcRII-a; fcRII-b; FCRIIC; FGFR2B; IGFR2; IgG Fc gamma receptor II; IgG Fc receptor II; IgG Fc receptor II-a; IgG Fc receptor II-b; IgG Fc receptor II-c; Immunoglobulin G Fc receptor II; immunoglobulin G Fc receptor II-c; Low affinity immunoglobulin gamma Fc region receptor II; Low affinity immunoglobulin gamma Fc region receptor II-a; Low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; MGC23887; MGC30032; RP11-5K23.6
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Vidéos
FDS
Documents
Certificats