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CD38 Mouse anti-Human, Brilliant Ultraviolet 737, Clone: HB7, BD Horizon™
Mouse Monoclonal Antibody
329.00€ - 710.00€
Spécification
Antigène | CD38 |
---|---|
Clone | HB7 |
Applications | Flow Cytometry |
Classification | Monoclonal |
Conjugué | Brilliant Ultraviolet 737 |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
---|---|---|---|---|---|---|---|---|---|
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
17267914
|
BD Biosciences
612825 |
25 Tests |
329.00€
25 tests |
Expédition estimée: 16-05-2024 Connectez-vous pour voir le stock disponible |
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17257914
|
BD Biosciences
612824 |
100 Tests |
710.00€
100 tests |
Expédition estimée: 16-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
The HB7 monoclonal antibody specifically binds to human CD38. CD38 is a type II transmembrane glycoprotein of 45 kDa with a protein core of 35 kDa. The CD38 antigen is expressed on essentially all pre-B lymphocytes, plasma cells, and thymocytes. It is also present on activated T lymphocytes, natural killer (NK) lymphocytes, myeloblasts, and erythroblasts. The antigen is expressed during the early stages of T- and B-lymphocyte differentiation, is lost during the intermediate stages of maturation, and then reappears during the final stages of maturation. The CD38 antigen is expressed on 90% of CD34+ cells, and is not expressed on pluripotent stem cells. Coexpression of CD38 antigen on CD34+ cells indicates lineage commitment of those cells. CD38 is a counter-receptor of CD31. It is also expressed in T- and B-acute lymphoblastic leukemia (ALL), Burkitt's lymphoma, multiple myeloma, acute myeloid leukemia (AML), and chronic lymphocytic leukemia (CLL).
The antibody was conjugated to BD Horizon BUV737 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes. This dye is a tandem fluorochrome of BD Horizon BUV395 with an Ex Max of 348-nm and an acceptor dye with an Em Max at 737-nm. BD Horizon Brilliant BUV737 can be excited by the ultraviolet laser (355 nm) and detected with a 740/35 filter. Due to the excitation of the acceptor dye by other laser lines, there may be significant spillover into channels detecting Alexa Fluor™ 700-like dyes (eg, 712/20-nm filter).
Spécification
CD38 | |
Flow Cytometry | |
Brilliant Ultraviolet 737 | |
RUO | |
Aqueous buffered solution containing ≤0.09% sodium azide. | |
IgG1 κ | |
Affinity Purified |
HB7 | |
Monoclonal | |
Mouse | |
Human | |
Human BJAB B cell line | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |