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CD49b (Integrin alpha 2) Rat anti-Mouse, PerCP-eFluor™ 710, Clone: DX5, eBioscience™

Rat Monoclonal Antibody

Marque:  Affymetrix eBioscience 46-5971-82

Code nomenclature Nacres: NA.41

Informations supplémentaires : Poids : 0.25000kg

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Code produit. 15331380

  • 280.00€ / 100µg

En stock, prêt à être expédié : 1

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Description

Description

For a filter configuration, we recommend using the 685 LP dichroic mirror and 710/40 band pass filter, however the 695/40 band pass filter is an acceptable alternative. Our testing indicates that PerCP-eFluor™ 710 conjugated antibodies are stable when stained samples are exposed to freshly prepared 2% formaldehyde overnight at 4°C, but please evaluate for alternative fixation protocols. Excitation: 488 nm; Emission: 710 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered. CD49b (Integrin alpha 2, Integrin alpha 2 chain, VLA-2 alpha chain, HM alpha 2) is a member of the integrin family. It is a glycoprotein with molecular weight of 150 kD, and it complexes with CD29 (Integrin beta 1) to form the heterodimeric integrin VLA-2 (integrin alpha 2 beta 1, or GPIa/IIa) complex. VLA-2 is an extracellular receptor for laminin, collagen, and fibronectin, and interaction with its ligands results in the activation of intracellular signaling pathways. It has reported roles in VEGF-induced angiogenesis in vivo, as well as adhesion and lymphocyte activation. CD49b is expressed by NK cells, NK-T cells, monocytes, platelets, and epithelial cells. It is also expressed on adaptive immune cells such as T and B cells, specifically on a subset of CD4+ T cells in the spleen, on intraepithelial and lamina propria lymphocytes in the intestine, as well as on a population of peripheral CD4+ type 1 T regulatory (Tr1) cells that co-express LAG-3.
Spécification

Spécification

CD49b (Integrin alpha 2)
Monoclonal
0.2 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q62469
BR, CD49B, GPIa, VLA-2, VLAA2, ITGA2
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
DX5
PerCP-eFluor™ 710
Itga2
Liquid
Itga2
IgM, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
16398
Vidéos
Documents

For Research Use Only.