Learn More
CD56 Mouse anti-Human, Brilliant Ultraviolet 737, Clone: NCAM16.2 (also known as NCAM 16), BD Horizon™
Mouse Monoclonal Antibody
354.00€ - 740.00€
Spécification
Antigène | CD56 |
---|---|
Clone | NCAM16.2 (also known as NCAM 16) |
Applications | Flow Cytometry |
Classification | Monoclonal |
Conjugué | Brilliant Ultraviolet 737 |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
---|---|---|---|---|---|---|---|---|---|
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
16835630
|
BD Biosciences
612767 |
25 Tests |
354.00€
1 pièce |
Expédition estimée: 16-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
17287864
|
BD Biosciences
612766 |
100 Tests |
740.00€
100 tests |
En stock Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
16609037
|
BD Biosciences
612766 |
100 Tests |
Cet article est actuellement indisponible ou discontinu.
Veuillez consulter la page produit pour de possible alternative dans l’onglet |
||||||
Description
The NCAM16.2 monoclonal antibody specifically binds to human CD56. It recognizes an extracellular immunoglobulin-like domain common to 120, 140, and 180 kDa forms of CD56, also known as the neural cell adhesion molecule (NCAM), NKH1 or MSK39. The CD56 antigen is expressed on approximately 10% to 25% of peripheral blood lymphocytes. It is present on essentially all resting and activated CD16+ natural killer (NK) lymphocytes and approximately 5% of CD3+ peripheral blood lymphocytes. CD3+ CD56+ T lymphocytes comprise a unique subset of cytotoxic T lymphocytes that mediates non-major histocompatibility complex (MHC)-restricted cytotoxicity. CD56 antigen density on NK lymphocytes increases upon cellular activation. The CD56 antigen is involved in neuronal homotypic cell adhesion and cell differentiation during embryogenesis. CD16+ CD56+ NK cells demonstrate reciprocal transfer of an activation state with dendritic cells.
The antibody was conjugated to BD Horizon™ BUV737 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes. This dye is a tandem fluorochrome of BD Horizon BUV395 with an Ex Max of 348-nm and an acceptor dye with an Em Max at 737-nm. BD Horizon Brilliant BUV737 can be excited by the ultraviolet laser (355 nm) and detected with a 740/35 filter. Due to the excitation of the acceptor dye by other laser lines, there may be significant spillover into channels detecting Alexa Fluor™ 700-like dyes (e.g., 712/20-nm filter).
Spécification
CD56 | |
Flow Cytometry | |
Brilliant Ultraviolet 737 | |
RUO | |
Aqueous buffered solution containing ≤0.09% sodium azide. | |
IgG2b κ | |
Affinity Purified |
NCAM16.2 (also known as NCAM 16) | |
Monoclonal | |
Mouse | |
Human | |
Immunoaffinity-enriched adult human brain NCAM | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |