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Cdc20 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 10252-1-AP-150UL
Informations supplémentaires : Poids : 0.00010kg
Description
Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.Spécification
Cdc20 | |
0.33 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
Q12834 | |
CDC20, CDC20A, p55CDC | |
Rabbit | |
IgG | |
150 μL | |
-20°C | |
Primary | |
991 |
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
Unconjugated | |
CDC20 | |
Liquid | |
CDC20 | |
Cdc20 Fusion Protein Ag0295 | |
Antigen Affinity Chromatography | |
RUO | |
Antibody | |
Polyclonal | |
Human |