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CHMP4B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 13683-1-AP-20UL
Informations supplémentaires : Poids : 0.00010kg
Description
This antibody is highly specific to the CHMP4B and it doesn't cross-react with other CHMPs as well as other CHMP4s (CHMP4A and CHMP4C).
CHMP4B is a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies.Spécification
CHMP4B | |
Polyclonal | |
Unconjugated | |
CHMP4B | |
C20orf178, CHMP4B, chromatin modifying protein 4B, CTPP3, hSnf7 2, hVps32 2, Shax1, SNF7, SNF7 2, Vps32 2 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
100359642, 128866, 75608 | |
-20°C | |
Liquid |
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence | |
0.2 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
Q9D8B3, Q9H444 | |
CHMP4B | |
CHMP4B Fusion Protein Ag4544 | |
20 μL | |
Primary | |
Mouse, Human, Rat | |
Antibody | |
IgG |