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ACROBiosystems Cynomolgus / Rhesus macaque CD27 / TNFRSF7 Protein, Mouse IgG2a Fc Tag, low endotoxin

low endotoxin

Marque:  ACROBiosystems CD7-C5259-100UG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15876247

  • 419.88€ / 100µg
Expédition estimée: 10-04-2024
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Description

Description

CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.

This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 46.2 kDa. The protein migrates as 50-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

XP_005569963.1
100 μg
Ala 20 - Arg 191
CD27,TNFRSF7,S152,T14,Tp55
Unconjugated
Mouse IgG Fc Tag
Less than 0.1 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
46.2 kDa
Cynomolgus / Rhesus macaque CD27, Mouse IgG2a Fc Tag, low endotoxin (CD7-C5259) is expressed from human 293 cells (HEK293). It contains AA Ala 20 - Arg 191 (Accession # XP_005569963.1). In the region Ala 20 - Arg 191, the AA sequence of Cynomolgus and Rhesus macaque CD27 are homologus.
-20°C
CD27
Cynomolgus Monkey, Rhesus Macaque
50 mM Tris, 100 mM Glycine, pH7.5
HEK293
Immune Checkpoint Proteins
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