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Desmoglein 2 Monoclonal Antibody (CSTEM28), Alexa Fluor™ 488, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

149.00€ - 359.00€

Spécification

Antigène Desmoglein 2
Clone CSTEM28
Concentration 0.5 mg/mL
Applications Flow Cytometry, Immunocytochemistry
Classification Monoclonal
Consulter d'autres spécifications

Produits 2
Code produit Marque Quantité Prix Quantité et disponibilité  
Code produit Marque Quantité Prix Quantité et disponibilité  
16381004
Afficher les documents Détails de la promotion
Affymetrix eBioscience
53-9159-82
100 μg
359.00€
100µg
Voir les produits de remplacement
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Expédition estimée: 16-04-2024
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16371004
Afficher les documents Détails de la promotion
Affymetrix eBioscience
53-9159-80
25 μg Cet article est actuellement indisponible ou discontinu. Veuillez consulter la page produit pour de possible alternative dans l’onglet
N/A Voir les produits de remplacement
Économisez jusqu'à 
»
Description

Description

This monoclonal antibody CSTEM28 reacts with human desmoglein 2 (DSG2), a type 1 transmembrane protein belonging to the cadherin family. DSG2 is expressed by epithelial cells, cardiomyocytes, endothelial progenitors, and CD34+CD45dim hematopoietic stem and progenitor cells. This adhesion molecule forms cell-cell adhesion complexes called desmosomes that provide tensile strength to tissues that experience mechanical stress. Other than its role in desmosome formation, DSG2 plays a role in barrier integrity, adhesion, migration, cell apoptosis, proliferation, vasculogenic mimicry, and intracellular signaling. DSG2-expressing endothelial progenitor cells are pro-angiogenic, suggesting a role in vasculature formation. On hematopoietic stem and progenitor cells, DSG2 expression is highest on CD38-CD90+ multi-potent cells. DSG2 expression is progressively decreased as a function of differentiation, with DSG2 expression absent on mature lymphocytes. DSG2 also serves as a receptor for adenoviruses and can be shed by mucosal barriers in the intestine. This CSTEM28 antibody has been tested by flow cytometric analysis of 2102ep cell line. This has also been tested by immunocytochemistry of fixed and permeabilized cells and can be used at less than or equal to 10 μg/mL. It is recommended the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 μm post-manufacturing filtered.

Desmoglein 2 Monoclonal antibody specifically detects Desmoglein 2 in Human samples. It is validated for Flow Cytometry, Immunocytochemistry.
Spécification

Spécification

Desmoglein 2
0.5 mg/mL
Monoclonal
Liquid
RUO
Q14126
DSG2
Primary
4° C, store in dark, DO NOT FREEZE!
DSG2
CSTEM28
Flow Cytometry, Immunocytochemistry
Alexa Fluor 488
Mouse
Human
1829
IgG2b κ
Affinity chromatography
Antibody
Vidéos
FDS
Documents

Documents

Product Certifications

For Research Use Only.